BNIP3

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human, Mouse
Applications	WB, IF, IHC
Protein Family	Apoptosis/Autophagy
Amount	100ug
Host	Rabbit
Item no.	A0584
eClass 6.1	32160702
eClass 9.0	32160702
Available
Calculated MW	22kDa
Immunogen	A synthetic peptide of human BNIP3
Synonyms	BNIP3, NIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Purity	Affinity purification
Storage Buffer	Store at 4C or -20C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2.
Illustration	Western blot analysis of extracts of mouse brain cell lines, using BNIP3antibody.
Gene Symbol	BNIP3
GeneID (Human)	664
GeneID	664
Protein MW	194
SWISS	Q12983
Route	Synthetic Peptide

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