DRD4

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human, Mouse
Applications	WB, IHC
Amount	100ug
Host	Rabbit
Item no.	A1337
eClass 6.1	32160702
eClass 9.0	32160702
Available
*	DESCRIPTION
Calculated MW	62kDa
Immunogen	A synthetic peptide of human DRD4
Gene ID	1815
Swiss Prot	P21917
Synonyms	DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 Receptor;
Isotype	IgG
Purity	Affinity purification
Storage Buffer	Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Recommended Dilutions	WB 1:500-1:1000 IHC 1:50-1:100 FC 1:20-1:50
illustration	Western blot analysis of extracts of mouse heartcelllines, using DRD4antibody.

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Amount: 100ug

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Delivery expected until 7/2/2024