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[KO Validated] PARP1 Rabbit pAb

[KO Validated] PARP1 Rabbit pAb

Manufacturer	Abclonal
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies CHiP small GTPases Arf Subfamily
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB, IF, ICC, ELISA
Amount	20ul
Host	Rabbit
Item no.	A0942-20ul
Targets	ARFRP1
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Background	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Route	Synthetic peptide
Manufacturers Category	Polyclonal Antibodies
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 81-390 of human PARP1 (NP_001609.2).
Storage	Store at -20℃. Avoid freeze / thaw cycles.\|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilution	WB, 1:1000 - 1:5000\|IF/ICC, 1:50 - 1:200
Protein Size	113kDa
Manufacturers Research Area	Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, DNA Damage Repair, RNA Binding, Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Centrosome, Death Receptor Signaling Pathway, Immunology Inflammation, NF-kB Signaling Pathway
Gene Symbol	PARP1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20ul

available

Delivery expected until 7/2/2024