GFRA1

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applications	WB, IHC
Amount	100ug
Host	Rabbit
Item no.	A2953
eClass 6.1	32160702
eClass 9.0	32160702
Available
*	DESCRIPTION
Calculated MW	51kDa
Immunogen	A synthetic peptide of human GFRA1
Gene ID	2674
Swiss Prot	P56159
Synonyms	DKFZp313E1012; DKFZp686J0156; FLJ10561; FLJ31546; GDNFR; GDNFRA; GFR-ALPHA-1; MGC23045; RET1L; RETL1; TRNR1
Isotype	IgG
Purity	Affinity purification
Storage Buffer	Store at -20? or -80?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009]
Recommended Dilutions	WB 1:500-1:2000 IHC 1:50-1:200
illustration	Western blot analysis of extracts of CEM cellline, using GFRA1antibody.

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Amount: 100ug

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Delivery expected until 7/2/2024