HMGA2 Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Recombinant fusion protein containing a sequence corresponding to amino acids 55-109 of human HMGA2 (NP_003474.1).

12kDa

Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation, Endocrine Metabolism, Neuroscience, Cell Type Marker, Stem Cells, Neural Stem Cells.

8091

HMGA2