Comparison

Phospho-SHP1-Y536 Rabbit pAb European Partner

Item no. AP0440-100ul
Manufacturer Abclonal
Amount 100 ul
Quantity options 100 ul 200 ul 20 uL 50 ul
Category
Type Antibody Polyclonal
Applications WB, IF, ICC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Purity Affinity purification
NCBI PTPN6
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, Phospho-SHP1-Y536
Similar products Phospho-PTPN6-Y536
Shipping Condition Cool pack
Available
Manufacturer - Category
Phosphorylated Antibodies
Shipping Temperature
ice pack
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.
Immunogen
A phospho specific peptide corresponding to residues surrounding Y536 of human PTPN6
Recommended Dilution
WB, 1:500 - 1:2000|IF/ICC, 1:100 - 1:200
Protein Size
68kDa
Route
Synthetic peptide
Manufacturer - Research Area
Protein phosphorylation, Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Immunology Inflammation, B Cell Receptor Signaling Pathway, Jak-Stat-IL-6 Receptor Signaling Pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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