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Pacritinib (SB1518) 25mg

Pacritinib (SB1518) 25mg

Item no.	A12694-25
Manufacturer	Adooq
CASRN	937272-79-2
Amount	25 mg
Quantity options	10 mg 100 mg 10mM x 1mL in DMSO 2 mg 25 mg 5 mg 50 mg 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	>98%
Smiles	C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC=CC(=C4)C5=NC(=NC=C5)NC(=C3)C=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SB-1518; SB 1518
Similar products	Pacritinib (SB1518)
Available
Storage Conditions	2 years at -20C
Molecular Weight	472, 58
Chemical Name	11-(2-pyrrolidin-1-yl-ethoxy)-14, 19-dioxa-5, 7, 26-triaza-tetracyclo[19.3.1.1(2, 6).1(8, 12)]heptacosa-1(25), 2(26), 3, 5, 8, 10, 12(27), 16, 21, 23-decaene
Description	Pacritinib, also known as SB1518, is an orally bioavailable inhibitor of Janus kinase 2 (JAK2) and the JAK2 mutant JAK2V617F with potential antineoplastic activity. Pacritinib competes with JAK2 for ATP binding, which may result in inhibition of JAK2 activation, inhibition of the JAK-STAT signaling pathway, and so caspase-dependent apoptosis.
Solubilty	DMSO

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 9/4/2025

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