SensoLyte® Generic MMP Assay Kit Colorimetric - 1 kit

Assay Kits

4 °C

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion as well as other diseases is well known. The SensoLyte Generic MMP Assay Kit can be used to detect the activity of a variety of MMPs, including MMP-1, 2, 3, 7, 8, 9, 12, 13, and 14 or for high throughput screening of MMPs' inducers and inhibitors. The substrate is a thiopeptolide that is cleaved by the MMPs, releasing a sulfhydryl group, which can be detected with a color-developing thiol-reactive agent, 4, 4'-dithiodipyridine or Ellman's Reagent at 412 nm using a microplate reader. The assays are performed in a convenient 96-well microplate format.

Adhesion & Extracellular Matrix; Cancer & Apoptosis / 0

5400535131746

nanogram

41105333