Comparison

Anti-BCMA bispecific antibody(DM4)

Item no. DIM-DMB100003-10ug
Manufacturer DIMA Biotechnology
Amount 10 ug
Quantity options 100 ug 100 uL 10 ug 10 ul 500 ug
Category
Type Antibody Primary
Format Lyophilized
Applications FC
Clone DM4
Specific against Human (Homo sapiens)
Host Rabbit
Isotype scFv
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias TNFRSF17
Shipping Condition Room temperature
Available
Manufacturer - Applications
Flow Cyt; MM Tumor cell killing
Manufacturer - Category
Monoclonal antibodies
Manufacturer - Targets
BCMA
Molecular Weight
20kDa
Buffer
50% Glycerol; PBS, pH 7.4; 0.1% BSA
Clonality
Monoclonal
Purification
Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions
Flow Cyt 1:100; MMTumor cell killing
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
BiTE bispecific antibody is an Engineered fusion protein constructed from two single-chain variable fragments (scFvs) of different monoclonal antibodies. One of the scFvs will be constructed from an anti-CD3 monoclonal antibody; and the other scFv fragment which linked by a linker region will be made from an anti-Tumor cell specific monoclonal antibody.The B-cell maturation protein (BCMA or BCM) is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes; and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily; member 13b (TNFSF13B:TALL-1:BAFF); and to lead to NF-kappaB and MAPK8:JNK activation. This receptor also binds to various TRAF family members; and thus may transduce signals for cell survival and proliferation. [provided by RefSeq; Jul 2008]
Immunogen
Recombinant human BCMA (Met1-Ala54) (PME100001) produced by using human HEK293 cells
Antigen
BCMA
Application Advice
Flow Cyt 1/100; MMTumor cell killing
Description
Anti-BCMA bispecific antibody(DM4)
Preservative
0.1% Procline 300
Reconstitution
Reconstitute with deionized water
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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