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Anti-CD38 antibody(DM28); Rabbit mAb

Anti-CD38 antibody(DM28); Rabbit mAb

Item no.	DIM-DME100027-10ug
Manufacturer	DIMA Biotechnology
Amount	10 ug
Quantity options	100 ug 100 uL 10 ug 10 ul 500 ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Hematology Leukemia Lymphoma Myeloma Flow Cytometry ELISA Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody Primary
Format	Lyophilized
Applications	WB, FC, IHC, ELISA
Clone	DM28
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	T10,cADPr hydrolase 1
Shipping Condition	Room temperature
Available
Manufacturer - Category	Monoclonal antibodies
Manufacturer - Targets	CD38
Molecular Weight	34kDa
Buffer	50% Glycerol; PBS, pH 7.4; 0.1% BSA
Clonality	Monoclonal
Purification	Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions	ELISA 1:5000-10000; Flow Cyt 1:100
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	CD antigen CD38 is also known as ADP-ribosyl cyclase 1; which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas; liver; kidney; brain; testis; ovary; placenta; malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses; metabolic disturbances; and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection; leukemias; myelomas; solid tumors; type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Immunogen	Recombinant human CD38 (Val43-IIe300)(PME100004) produced by using human HEK293 cells
Antigen	CD38
Application Advice	ELISA 1/5000-10000; Flow Cyt 1/100
Description	Anti-CD38 antibody(DM28); Rabbit mAb
Preservative	0.1% Procline 300
Reconstitution	Reconstitute with deionized water
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 10/30/2025

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