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Anti-B7-H3 antibody(DM53); Rabbit mAb

Anti-B7-H3 antibody(DM53); Rabbit mAb

Item no.	DIM-DME100053-100ug
Manufacturer	DIMA Biotechnology
Amount	100 ug
Quantity options	100 uL 100 ug 10 uL 10 ug 500 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Melanoma Sarcoma Mesothelioma Flow Cytometry ELISA Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	FC, ELISA
Clone	DM53
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	B7-H3,CD276,B7 homolog 3,B7H3
Shipping Condition	Room temperature
Available
Manufacturer - Category	Monoclonal antibodies
Manufacturer - Targets	B7-H3
Molecular Weight	57 kDa
Buffer	50% Glycerol; PBS, pH 7.4; 0.1% BSA
Clonality	Monoclonal
Purification	Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions	ELISA 1:5000-10000; Flow Cyt 1:100
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene belongs to the immunoglobulin superfamily; and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors; the protein is preferentially expressed only in tumor tissues. Additionally; it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA; and there is an inverse correlation between the expression of this protein and miR29 levels; suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen	Recombinant human B7H3(Leu29-Pro245) (PME100012) produced by using human HEK293 cells
Antigen	B7H3
Application Advice	ELISA 1/5000-10000; Flow Cyt 1/100
Description	Anti-B7-H3 antibody(DM53); Rabbit mAb
Preservative	0.1% Procline 300
Reconstitution	Reconstitute with deionized water
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/30/2025

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