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MAFK Antibody

MAFK Antibody

Item no.	OAGA07445
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Hematology Leukemia Myeloma Immunoprecipitation Western Blot Primary Antibodies CHiP Neuronal Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IP, CHIP
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	P18,NFE2U
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Suggested starting dilutions are as follows: IP: 1:100-1:500, WB: 1:500-1:3000, ChIP assay. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene symbol	MAFK
Gene Fullname	MAF bZIP transcription factor K
Product format	Liquid
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008]
Nucleotide accession_num	NM_002360.3
Protein accession_num	NP_002351.1
Protein name	transcription factor MafK
Clonality	Polyclonal
Purification	Purified by antigen-affinity chromatography.
Immunogen	Full length human MAFK Recombinant protein.
Concentration	1 mg/ml
Storage Buffer	1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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