Comparison

IGF1R Antibody (Phospho-Tyr1161)

Item no. OASG03735
Manufacturer AVIVA Systems Biology
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias IGFR,CD221,IGFIR,JTK13
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Manufacturer - Targets
Phospho-Tyr1161
Shipping Temperature
Wet Ice
Manufacturer - Application Additional Information
WB: 1:500~2000IHC: 1:100~300IF: 1:200~1000ELISA: 1:40000
Gene symbol
IGF1R, INSR
Gene Fullname
insulin-like growth factor 1 receptor
Protein size
1100-1180aa
Product format
Liquid PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and storage
Store at -20°C for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.
Description of target
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit anti-serum by affinity-chromatograhy.
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human IGF-IR (phospho Tyr1161)
Manufacturer - Specificity
Phospho-IGF-IR-Tyr1161 polyclonal antibody (Insulin-like growth factor 1 receptor and Insulin receptor) binds to endogenous Insulin-like growth factor 1 receptor and Insulin receptor at the amino acid region 1100-1180 only when phosphorylated at Tyr1
Concentration
1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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