« Back
Home /
Anti-Histone H3 Rabbit mAb

Anti-Histone H3 Rabbit mAb

Item no.	PTM-6613
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized powder
Applications	WB, IHC-P
Clone	JMMR-2423B
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Xiao Cheng, et al. Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis. iScience, 2024. https://www.cell.com/iscience/fulltext/S2589-0042(24)01501-3.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Histone H3.1,Histone H3/a,H3C1,H3FA,HIST1H3A,Histone H3/b,Histone H3/c,Histone H3/d
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Histone & Histone Modification Antibodies, Loading Control Antibodies
Manufacturer - Targets	Histone H3
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	15
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Epigenetics
Product description	Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10, Ser28, and Thr11 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
Purification Method	Protein A purified
Manufacturer - Specificity	Anti-Histone H3 Rabbit mAb detects endogenous levels of total histone H3 protein. It does not cross-react with other histone or non-histone proteins.
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Immunogen	Synthetic peptide derived from human histone H3 protein
Clonality	Recombinant Monoclonal
Background	Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10, Ser28, and Thr11 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
Cellular Localization	Nucleus

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ul

available

Delivery expected until 2/19/2026

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer