Ezrin Rabbit mAb

Monoclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human Ezrin (P15311).

69kDa

Epigenetics Nuclear Signaling, RNA Binding, Protein phosphorylation, Cancer, Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Immunology Inflammation, B Cell Receptor Signaling Pathway.

7430

EZR