OAS1 Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This interferon-induced gene encodes a protein that synthesizes 2', 5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human OAS1 (NP_058132.2).

46kDa

Epigenetics Nuclear Signaling.

4938

OAS1