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Filamin A Rabbit mAb

Filamin A Rabbit mAb

Manufacturer	Abclonal
Category	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies Obesity Immunohistochemistry Western Blot Cardiovascular Research Thrombosis & Hemostasis Atherosclerosis Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Monoclonal
Specific against	Human
Isotype	IgG
Applications	WB, ELISA, IHC-P
Amount	20ul
Host	Rabbit
Item no.	A3738-20ul
Targets	CLMP;;FLNA
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	42030590
Available
Background	The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Route	Synthetic Peptide
Manufacturers Category	Monoclonal Antibodies
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 2548-2647 of human Filamin A (P21333).
Storage	Store at -20℃. Avoid freeze / thaw cycles.\|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilution	WB, 1:500 - 1:2000\|IHC-P, 1:100 - 1:500
Protein Size	281kDa
Manufacturers Research Area	Epigenetics Nuclear Signaling, RNA Binding, Protein phosphorylation, Signal Transduction, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Actins
Gene Symbol	FLNA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20ul

available

Delivery expected until 5/28/2024