NDRG1 Rabbit mAb

Monoclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

A synthetic peptide corresponding to a sequence within amino acids 295-394 of human NDRG1 (Q92597).

43kDa

Epigenetics Nuclear Signaling, Protein phosphorylation, Cancer, Invasion and Metastasis, Signal Transduction, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Angiogenesis.

10397

NDRG1