CYP51A1 Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of CYP51A1 (NP_000777.1).

57kDa

Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Lipid Metabolism, Cholesterol Metabolism, Lipases, Drug metabolism, Cardiovascular, Lipids.

1595

CYP51A1