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Glutaredoxin 1 Antibody (Clone 28C3)

Glutaredoxin 1 Antibody (Clone 28C3)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Clone	Clone 28C3
Applications	IP, ELISA
Amount	100 ul
Host	Mouse
Item no.	ABC-ABV11173-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	P35754
Application	E, IP
Bio Background	Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress. Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Clonality	Monoclonal
Gene ID	2745
Gene Name	GLRX
Subtitle	Mouse Monoclonal Antibody
Reactivity	H
Legend image 1	IP analysis of Jurkat cell lysates. Lane 1: Input, Lane 2: Precipitated sample
Type image 1	IP
	Clone: Clone 28C3
Concentration (mg/ml)	1 mg/ml

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ABC-ABV11173-100-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 7/4/2024