KRT80 Antibody (C-term)

Synthetic Peptide

Keratins are intermediate filament proteins responsible
for the structural integrity of epithelial cells and are subdivided
into epithelial keratins and hair keratins. This gene's expression
profile shows that it encodes a type II epithelial keratin,
although structurally the encoded protein is more like a type II
hair keratin. This protein is involved in cell differentiation,
localizing near desmosomal plaques in earlier stages of
differentiation but then dispersing throughout the cytoplasm in
terminally differentiating cells. The type II keratins are
clustered in a region of chromosome 12q13. Two transcript variants
encoding two different fully functional isoforms have been found
for this gene.

Polyclonal

144501

Affinity Purified Rabbit Polyclonal Antibody (Pab)

KRT80 Antibody (C-term) (Cat. #AP10874b) western blot analysis in NCI-H460, SK-BR-3 cell line lysates (35ug/lane).This demonstrates the KRT80 antibody detected the KRT80 protein (arrow).

1:1000

Rabbit Ig

404-432

This KRT80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human KRT80.