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FGL1 Antibody (C-term)

FGL1 Antibody (C-term)

Item no.	ABC-AP12647b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FGL1, HFREP1, Fibrinogen-like protein 1, HP-041, Hepassocin, Hepatocyte-derived fibrinogen-related protein 1, Liver fibrinogen-related protein 1, HFREP-1, LFIRE-1
Available
Primary Accession	Q08830
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
Bio References	Bailey, S.D., et al. Diabetes Care (2010) In press : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Yu, H.T., et al. J. Biol. Chem. 284(20):13335-13347(2009)
Clonality	Polyclonal
Clone/Animal Names	RB19507
Gene ID	2267
Gene Name	FGL1 {ECO:0000303\|PubMed:18039467, ECO:0000312\|HGNC:HGNC:3695}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysate from HepG2 cell line, using FGL1 Antibody (C-term)(Cat. #AP12647b). AP12647b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	FGL1 Antibody (C-term) (Cat. #AP12647b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FGL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_671736.2; NP_963847.1
Isotype	Rabbit Ig
Calculated MW	36379
Antigen Region	218-247
Antigen Source	HUMAN
Target/Specificity	This FGL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the C-terminal region of human FGL1.
NCBI Accession	NP_004458.3; NP_671736.2; NP_963846.1; NP_963847.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/4/2025

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