Bio Background |
HAUS8 is 1 of 8 subunits of the 390-kD human augmincomplex, or HAUS complex. The augmin complex was first identifiedin Drosophila, and its name comes from the Latin verb 'augmentare, 'meaning 'to increase.' The augmin complex is a microtubule-bindingcomplex involved in microtubule generation within the mitoticspindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed19369198]). |
Bio References |
Wu, G., et al. Mol. Biol. Cell 20(22):4686-4695(2009)Lawo, S., et al. Curr. Biol. 19(10):816-826(2009)Uehara, R., et al. Proc. Natl. Acad. Sci. U.S.A. 106(17):6998-7003(2009)Wu, G., et al. Mol. Cell. Biol. 28(11):3652-3662(2008)Goshima, G., et al. J. Cell Biol. 181(3):421-429(2008) |