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ACTA2 Antibody (monoclonal) (M02)

ACTA2 Antibody (monoclonal) (M02)

Item no.	ABC-AT1030a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ELISA
Clone	4A8-2H3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	1.Isolation and Characterization of a Primary Proximal Tubular Epithelial Cell Model from Human Kidney by CD10/CD13 Double Labeling.Van der Hauwaert C, Savary G, Gnemmi V, Glowacki F, Pottier N, Bouillez A, Maboudou P, Zini L, Leroy X, Cauffiez C, Perrais M, Aubert SPLoS One. 2013 Jun 14;8(6):e66750. doi: 10.1371/journal.pone.0066750. Print 2013.2.miR-199a-5p Is Upregulated during Fibrogenic Response to Tissue Injury and Mediates TGFbeta-Induced Lung Fibroblast Activation by Targeting Caveolin-1.Lino Cardenas CL, Henaoui IS, Courcot E, Roderburg C, Cauffiez C, Aubert S, Copin MC, Wallaert B, Glowacki F, Dewaeles E, Milosevic J, Maurizio J, Tedrow J, Marcet B, Lo-Guidice JM, Kaminski N, Barbry P, Luedde T, Perrais M, Mari B, Pottier NPLoS Genet. 2013 Feb;9(2):e1003291. doi: 10.1371/journal.pgen.1003291. Epub 2013 Feb 14.
NCBI	NP_001135417.1,NP_001604.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Actin,aortic smooth muscle,Alpha-actin-2,Cell growth-inhibiting gene 46 protein,ACTA2,ACTSA,ACTVS
Similar products	Alpha-actin-2, Actin, ACTA2, ACTSA, ACTVS, aortic smooth muscle, Cell growth-inhibiting gene 46 protein
Available
Manufacturer - Targets	ACTA2 (AAH17554.1, 1 a.a. ~ 377 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Clonality	Monoclonal
Gene Name	ACTA2
Subtitle	Mouse monoclonal antibody raised against a full length recombinant ACTA2.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH17554.1
Gene Description	actin, alpha 2, smooth muscle, aorta
Gene Summary	The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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