Comparison

S100A6 Antibody (monoclonal) (M16)

Item no. ABC-AT3760a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications WB, ELISA
Clone 6D1
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products S100A6, CACY, PRA, S100 calcium-binding protein A6, Calcyclin, Prolactin receptor-associated protein, Protein S100-A6, Growth factor-inducible protein 2A9, MLN 4
Available
Primary Accession
P06703
Antigen Type
Recombinant Protein
Application
WB, E
Bio Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Bio References
1.Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell-Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4.Volonte A, Di Tomaso T, Spinelli M, Todaro M, Sanvito F, Albarello L, Bissolati M, Ghirardelli L, Orsenigo E, Ferrone S, Doglioni C, Stassi G, Dellabona P, Staudacher C, Parmiani G, Maccalli CJ Immunol. 2013 Nov 25.2.S100A6 Overexpression Associates with Poor Prognosis and Is Epigenetically Up-Regulated in Gastric Cancer.Wang XH, Zhang LH, Zhong XY, Xing XF, Liu YQ, Niu ZJ, Peng Y, Du H, Zhang GG, Hu Y, Liu N, Zhu YB, Ge SH, Zhao W, Lu AP, Li JY, Ji JF.Am J Pathol. 2010 Jun 25. [Epub ahead of print]3.Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients.Di Tomaso T, Mazzoleni S, Wang E, Sovena G, Clavenna D, Franzin A, Mortini P, Ferrone S, Doglioni C, Marincola FM, Galli R, Parmiani G, Maccalli C.Clin Cancer Res. 2010 Feb 1; 16(3):800-13. Epub 2010 Jan 26.
Clonality
Monoclonal
Gene ID
6277
Gene Name
S100A6
Subtitle
Mouse monoclonal antibody raised against a partial recombinant S100A6.
Reactivity
H
Legend image 1
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (33.77 KDa) .
Type image 1
WB
Dilution image 1
1:500~1000
Legend image 2
S100A6 monoclonal antibody (M16), clone 6D1 Western Blot analysis of S100A6 expression in HeLa ( (Cat # AT3760a )
Type image 2
WB
Dilution image 2
1:500~1000
Legend image 3
Western Blot analysis of S100A6 expression in transfected 293T cell line by S100A6 monoclonal antibody (M16), clone 6D1.

Lane 1: S100A6 transfected lysate(10.2 KDa).
Lane 2: Non-transfected lysate.
Type image 3
WB
Dilution image 3
1:500~1000
Legend image 4
Detection limit for recombinant GST tagged S100A6 is approximately 0.03ng/ml as a capture antibody.
Type image 4
E
Other Accession
NM_014624
Isotype
IgG2a Kappa
Antigen Source
Human: ~~ Positive
Target/Specificity
S100A6 (NP_055439, 18 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession
NP_055439.1
Clone: 6D1
Org Accession
NP_055439
Gene Description
S100 calcium binding protein A6
Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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