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SUFU polyclonal antibody

SUFU polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Specific against	Human
Applications	WB, IHC, ICC
Amount	50ul
Host	Rabbit
Item no.	BS91299-50
Targets	SUFU
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	Q9UMX1(Human)
Application_all	WB:1:500-1:1, 000 ICC:1:50-1:200 IHC:1:50-1:200
Background	Su(fu) (for Suppressor-of-Fused) is a key negative regulator in the vertebrate Hedgehog signaling pathway. Su(fu) interacts with genes encoding proteins in this signal transduction pathway. In Drosophila, Intracellular transduction of the Hedgehog pathway involves the release of a large complex containing Su(fu). Su(fu) inhibits the activity of the transcription factor Gli1 and interacts with Gli2, Gli3 and the serine/threonine kinase Fused. Su(fu) is widely expressed in adult and embryonic tissues with higher expression in tissues patterned by hegdehog signaling. The Su(fu) gene locus maps to a region that is deleted in glioblastomas, prostate cancer, malignant melanoma and endometrial cancer.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	Protein affinity purified.
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Specificity	SUFU polyclonal antibody detects endogenous levels of SUFU protein.
BiowMW	54 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein with human SUFU aa 1-250.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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