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Synuclein alpha (Phospho-S129) polyclonal antibody

Synuclein alpha (Phospho-S129) polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Autophagy Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, IF, IHC, ICC
Amount	50ul
Host	Rabbit
Item no.	BS94008-50
Targets	APP ;;PRKN;;SNCA;;SRCIN1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P37840(Human) O55042(Mouse) P37377(Rat)
Application_all	ICC:1:50-1:200 IHC:1:50-1:200 WB:1:500
Background	The synuclein family members, including alpha-synuclein (also designated NACP for non-beta-Amyloid component) and beta-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. alpha-synuclein is localized to neuronal cell bodies and synapses. alpha-synuclein was first identified as a component of Alzheimer's disease amyloid plaques. Abnormal platelet function in Alzheimer's disease has been demonstrated. During megakaryocytic differentiation alpha-synuclein has been found to be upregulated, while beta-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of alpha-synuclein has been found in patients with early onset Parkinson's disease.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	Synuclein alpha (Phospho-S129) polyclonal antibody detects endogenous levels of Synuclein alpha protein only when phosphorylated at S129.
BiowMW	14 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic phospho-peptide corresponding to residues surrounding Ser129 of human alpha Synuclein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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