BNIP3L Antibody

Polyclonal Antibody

BNIP3L

Adenovirus E1B19k binding protein B5 antibody, Adenovirus E1B19K-binding protein B5 antibody, BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibody, BCL2/adenovirus E1B 19kDa interacting protein 3 like antibody, BNI3L_HUMAN antibody, BNIP3a antibody, BNIP3H antibody, BNIP3L antibody, BNIP3L protein antibody, NIP3 like protein X antibody, NIP3-like protein X antibody, NIP3L antibody, NIX antibody

Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein (1-187AA)

Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.

Antigen Affinity Purified

Cell Biology

Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein (1-187AA)