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DNMT3A Antibody

DNMT3A Antibody

Item no.	CSB-PA007083LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Oncology Neuroscience Neural Epigenetics Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA (cytosine 5) methyltransferase 3 alpha antibody; DNA (cytosine 5) methyltransferase 3A antibody; DNA (cytosine-5)-methyltransferase 3A antibody; DNA cytosine methyltransferase 3A2 antibody; DNA methyltransferase 3 alpha antibody; DNA methyltransferase 3a antibody; DNA methyltransferase HsaIIIA antibody; DNA MTase HsaIIIA antibody; DNM3A_HUMAN antibody; DNMT 3a antibody; DNMT antibody; Dnmt3a antibody; DNMT3A2 antibody; M.HsaIIIA antibody; MCMT antibody; OTTHUMP00000201149 antibody; TBRS antibody
Similar products	DNMT3A, DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	DNMT3A
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	DNA (cytosine 5) methyltransferase 3 alpha antibody; DNA (cytosine 5) methyltransferase 3A antibody; DNA (cytosine-5)-methyltransferase 3A antibody; DNA cytosine methyltransferase 3A2 antibody; DNA methyltransferase 3 alpha antibody; DNA methyltransferase 3a antibody; DNA methyltransferase HsaIIIA antibody; DNA MTase HsaIIIA antibody; DNM3A_HUMAN antibody; DNMT 3a antibody; DNMT antibody; Dnmt3a antibody; DNMT3A2 antibody; M.HsaIIIA antibody; MCMT antibody; OTTHUMP00000201149 antibody; TBRS antibody
Immunogen Species	Human
Immunogen	Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:200
Background	Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/16/2025

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