FFAR1 Antibody

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Recombinant Human Free fatty acid receptor 1 protein (143-178AA)

G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

>95%, Protein G purified

Signal Transduction

Recombinant Human Free fatty acid receptor 1 protein (143-178AA)