GIT1 Antibody, Biotin conjugated

Polyclonal Antibody

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Human

GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis, the function may involve SDCCAG3 and PTPN13 (By similarity).

>95%, Protein G purified

Signal Transduction

Recombinant Human ARF GTPase-activating protein GIT1 protein (470-642AA)