Comparison

H2AFX (Ab-139) Antibody

Item no. CSB-PA010097OA139nphHU-50ul
Manufacturer Cusabio
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, IHC, ELISA, CHIP
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias H2A histone family member X antibody; H2A histone family member X antibody; H2A.FX antibody; H2A.X antibody; H2a/x antibody; H2AFX antibody; H2AX antibody; H2AX_HUMAN antibody; Histone H2A.X antibody
Similar products H2AFX, H2AX, Histone H2AX (H2a/x) (Histone H2A.X)
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
H2AFX
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species
Human
Immunogen
Peptide sequence around site of Ser (139) derived from Human Histone H2AX
Dilution
ELISA:1:2000-1:10000
WB:1:50-1:500
IHC:1:20-1:200
IF:1:1-1:10
Background
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method
Antigen Affinity Purified
General Research Areas
Epigenetics and Nuclear Signaling
Initial Research Areas
Epigenetics and Nuclear Signaling
Antigen Species
Human
Antigen
Peptide sequence around site of Ser (139) derived from Human Histone H2AX
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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