Phospho-GAP43 (Ser41) Antibody

GAP43

Axonal membrane protein GAP 43 antibody; Axonal membrane protein GAP-43 antibody; B 50 antibody; Calmodulin binding protein P 57 antibody; F1 antibody; GAP 43 antibody; GAP43 antibody; Growth Associated Protein 43 antibody; Growth-associated protein 43 antibody; Nerve Growth Related Peptide antibody; Nerve growth related peptide GAP43 antibody; NEUM_HUMAN antibody; Neural phosphoprotein B 50 antibody; Neural phosphoprotein B-50 antibody; Neuromodulin antibody; Neuron growth associated protein 43 antibody; PP46 antibody; Protein F1 antibody; QtrA-11580 antibody; QtrA-13071 antibody

Peptide sequence around phosphorylation site of Ser41 (Q-A-S(p)-F-R) derived from Human GAP43.

GAP43 encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Rachael L. Neve, et, al. (1998) J. Neurosci, 18: 7757.
Yiping Shen, et, al. (2002) J. Neurosci, 22: 239.
Chantal Gamby, et, al. (1996) J. Biol. Chem, 271: 26698.

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugateds. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Neuroscience

Peptide sequence around phosphorylation site of Ser41 (Q-A-S(p)-F-R) derived from Human GAP43.