KDM5C Antibody

KDM5C

DXS1272E antibody; Histone demethylase JARID1C antibody; JARID1C antibody; JmjC domain containing protein SMCX antibody; Jumonji AT rich interactive domain 1C antibody; Jumonji, AT rich interactive domain 1C (RBP2 like) antibody; Jumonji/ARID domain-containing protein 1C antibody; KDM5C antibody; KDM5C_HUMAN antibody; Lysine (K) specific demethylase 5C antibody; Lysine-specific demethylase 5C antibody; MRX13 antibody; MRXJ antibody; MRXSCJ antibody; MRXSJ antibody; Protein SmcX antibody; Protein Xe169 antibody; rbp2 like protein antibody; Selected cDNA on X antibody; SMCX antibody; Smcx homolog X chromosome antibody; SmcX protein antibody; Smcy homolog X linked antibody; XE169 antibody; Xe169 protein antibody

Recombinant Human Lysine-specific demethylase 5C protein (45-324AA)

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).

>95%, Protein G purified

Epigenetics and Nuclear Signaling

Recombinant Human Lysine-specific demethylase 5C protein (45-324AA)