DYNLL1 Antibody

DYNLL1

8 kDa dynein light chain antibody; 8kDLC antibody; Cytoplasmic dynein light polypeptide antibody; DLC1 antibody; DLC8 antibody; DNCL1 antibody; DNCLC1 antibody; DYL1_HUMAN antibody; Dynein ; cytoplasmic; light chain 1 antibody; Dynein light chain 1 cytoplasmic antibody; Dynein light chain 1; cytoplasmic antibody; Dynein light chain LC8 type 1 antibody; Dynein light chain LC8-type 1 antibody; Dynein; cytoplasmic; light polypeptide 1 antibody; Dynein; light chain; LC8-type 1 antibody; DYNLL1 antibody; HDLC1 antibody; LC8 antibody; LC8a antibody; MGC126137 antibody; MGC126138 antibody; MGC72986 antibody; PIN antibody; Protein inhibitor of neuronal nitric oxide synthase antibody; Protein inhibitor of neuronal NOS antibody

Recombinant Human Dynein light chain 1, cytoplasmic protein (1-89AA)

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.

>95%, Protein G purified

Human

Polyclonal