MYO1G Antibody

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Recombinant Human Unconventional myosin-Ig protein (209-389AA)

Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.

>95%, Protein G purified

Signal Transduction

Recombinant Human Unconventional myosin-Ig protein (209-389AA)