DCSTAMP Antibody

DCSTAMP

DC-STAMP antibody; DCSTAMP antibody; DCSTP_HUMAN antibody; Dendritic cell-specific transmembrane protein antibody; Dendrocyte-expressed seven transmembrane protein antibody; FIND antibody; hDC-STAMP antibody; IL-Four INDuced antibody; IL-four-induced protein antibody; Transmembrane 7 superfamily member 4 antibody

Recombinant Human Dendritic cell-specific transmembrane protein (119-209AA)

Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

>95%, Protein G purified

Human

Polyclonal