UBASH3A Antibody

UBASH3A

Cbl interacting protein 4 antibody; Cbl-interacting protein 4 antibody; CLIP4 antibody; STS 2 antibody; STS-2 antibody; Suppressor of T cell receptor signaling 2 antibody; Suppressor of T-cell receptor signaling 2 antibody; T cell ubiquitin ligand antibody; T cell ubiquitin ligand protein antibody; T-cell ubiquitin ligand 1 antibody; TULA antibody; TULA-1 antibody; UBASH3A antibody; ubiquitin associated and SH3 domain containing, A antibody; Ubiquitin-associated and SH3 domain-containing protein A antibody; UBS3A_HUMAN antibody

Recombinant Human Ubiquitin-associated and SH3 domain-containing protein A protein (287-455AA)

Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

>95%, Protein G purified

Cell Biology

Recombinant Human Ubiquitin-associated and SH3 domain-containing protein A protein (287-455AA)