Comparison

ARPC3 Antibody

Item no. CSB-PA03324A0Rb-50ug
Manufacturer Cusabio
Amount 50 ug
Quantity options 100 ug 20 ug 50 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ARPC3 antibody; ARC21Actin-related protein 2/3 complex subunit 3 antibody; Arp2/3 complex 21 kDa subunit antibody; p21-ARC antibody
Similar products ARPC3, ARC21, Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
ARPC3
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species
Human
Immunogen
Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
Dilution
ELISA:1:2000-1:10000
WB:1:500-1:5000
IHC:1:20-1:200
IF:1:50-1:200
Background
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Signal Transduction
Initial Research Areas
Signal Transduction
Antigen Species
Human
Antigen
Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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