Comparison

PTEN Antibody

Item no. CSB-PA087229-50ul
Manufacturer Cusabio
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 10q23del antibody,BZS antibody,DEC antibody,GLM2 antibody,MGC11227 antibody,MHAM antibody,MMAC1 antibody,MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody,Mutated in multiple advanced cancers 1 antibody,Phosphatase and tensin homolog antibody,Phosphatase and tensin like protein antibody,Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN antibody,Pten antibody,PTEN_HUMAN antibody,PTEN1 antibody,TEP1 antibody
Similar products phosphatase and tensin homolog
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100
Manufacturer - Targets
PTEN
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
10q23del antibody, BZS antibody, DEC antibody, GLM2 antibody, MGC11227 antibody, MHAM antibody, MMAC1 antibody, MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody, Mutated in multiple advanced cancers 1 antibody, Phosphatase and tensin homolog antibody, Phosphatase and tensin like protein antibody, Phosphatidylinositol 3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN antibody, Pten antibody, PTEN_HUMAN antibody, PTEN1 antibody, TEP1 antibody
Immunogen Species
Human
Immunogen
Synthetic peptide of human PTEN
Dilution
ELISA:1:1000-1:5000
WB:1:200-1:1000
IHC:1:25-1:100
Background
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
Buffer
pH7.4 of PBS, 0.05% NaN3, 40% Glycerol.
Purification Method
Antigen Affinity Purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Synthetic peptide of Human PTEN
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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