Comparison

C3 Antibody

Item no. CSB-PA10599A0Rb-50ug
Manufacturer Cusabio
Amount 50 ug
Quantity options 100 ug 20 ug 50 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications IF, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ASP antibody; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody; C3 antibody; C3adesArg antibody; C3bc antibody; CO3_HUMAN antibody; Complement C3c alpha'' chain fragment 2 antibody
Similar products C3, Complement C3b alpha' chain, Complement C3c alpha' chain fragment 1, Complement C3d fragment, Complement C3dg fragment, Complement C3g fragment, CPAMD1, C3a anaphylatoxin, Complement C3 alpha chain, Complement C3f fragment, Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain, C3-beta-c (C3bc), Acylation stimulating protein (ASP) (C3adesArg), Complement C3c alpha' chain fragment 2]
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
C3
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species
Human
Immunogen
Recombinant Human Complement C3 protein (26-225AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:50-1:500
IF:1:50-1:200
Background
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Acylation stimulating protein (ASP): adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for GPR77. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of GPR77.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Immunology
Initial Research Areas
Immunology
Antigen Species
Human
Antigen
Recombinant Human Complement C3 protein (26-225AA)
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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