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PRKRA Antibody

PRKRA Antibody

Item no.	CSB-PA13669A0Rb-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DYT16 antibody; HSD14 antibody; Interferon inducible double stranded RNA dependent protein kinase activator A antibody; interferon-inducible double stranded RNA-dependent activator antibody; Interferon-inducible double stranded RNA-dependent protein kinase activator A antibody; PACT antibody; PKR associated protein X antibody; PKR associating protein X antibody; PKR-associated protein X antibody; PKR-associating protein X antibody; PRKRA antibody; PRKRA_HUMAN antibody; Protein activator of the interferon induced protein kinase antibody; Protein activator of the interferon-induced protein kinase antibody; Protein kinase antibody; Protein kinase interferon inducible double stranded RNA dependent activator antibody; RAX antibody
Similar products	PRKRA, Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator), PACT RAX
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	PRKRA
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	DYT16 antibody; HSD14 antibody; Interferon inducible double stranded RNA dependent protein kinase activator A antibody; interferon-inducible double stranded RNA-dependent activator antibody; Interferon-inducible double stranded RNA-dependent protein kinase activator A antibody; PACT antibody; PKR associated protein X antibody; PKR associating protein X antibody; PKR-associated protein X antibody; PKR-associating protein X antibody; PRKRA antibody; PRKRA_HUMAN antibody; Protein activator of the interferon induced protein kinase antibody; Protein activator of the interferon-induced protein kinase antibody; Protein kinase antibody; Protein kinase interferon inducible double stranded RNA dependent activator antibody; RAX antibody
Immunogen Species	Human
Immunogen	Recombinant Human Interferon-inducible double-stranded RNA-dependent protein kinase activator A protein (1-313AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:500
Background	Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at 'Lys-386' at 'Ser-392' respectively and enhances its activity in a EIF2AK2/PKR-dependent manner (By similarity).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Interferon-inducible double-stranded RNA-dependent protein kinase activator A protein (1-313AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 8/28/2025

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