PAK7 Antibody

Polyclonal Antibody

PAK5

EC 2.7.11.1 antibody, KIAA1264 antibody, MGC26232 antibody, p21 activated kinase 7 antibody, p21 protein (Cdc42/Rac)-activated kinase 7 antibody, p21(CDKN1A) activated kinase 7 antibody, p21-activated kinase 5 antibody, p21-activated kinase 7 antibody, PAK 5 antibody, PAK 7 antibody, PAK-5 antibody, PAK-7 antibody, PAK5 antibody, PAK7 antibody, PAK7_HUMAN antibody, Protein kinase PAK5 antibody, Serine/threonine protein kinase PAK 7 antibody, Serine/threonine-protein kinase PAK 7 antibody

Fusion protein of human PAK7

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Antigen Affinity Purified

Cell Biology

Fusion protein of Human PAK7