ANLN Antibody

Polyclonal Antibody

ANLN

Actin binding protein scraps homolog Drosophila antibody, Actin binding protein anillin antibody, Actin-binding protein anillin antibody, Anillin actin binding protein antibody, anln antibody, ANLN_HUMAN antibody, DKFZp779A055 antibody, FSGS8 antibody, Scra antibody, Scraps antibody, Scraps homolog antibody

Fusion protein of human ANLN

Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis.

Antigen Affinity Purified

Cell Biology

Fusion protein of Human ANLN