TNIP3 Antibody

ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Synthetic peptide of human TNIP3

TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Antigen Affinity Purified

Signal Transduction

Synthetic peptide of Human TNIP3