PTPN11 Antibody

Polyclonal Antibody

PTPN11

BPTP3 antibody, CFC antibody, JMML antibody, METCDS antibody, MGC14433 antibody, NS1 antibody, OTTHUMP00000166107 antibody, OTTHUMP00000166108 antibody, Protein tyrosine phosphatase 2 antibody, Protein tyrosine phosphatase 2C antibody, Protein tyrosine phosphatase non receptor type 11 antibody, Protein-tyrosine phosphatase 1D antibody, Protein-tyrosine phosphatase 2C antibody, PTN11_HUMAN antibody, PTP-1D antibody, PTP-2C antibody, PTP1D antibody, PTP2C antibody, PTPN11 antibody, SAP2 antibody, SH-PTP2 antibody, SH-PTP3 antibody, SH2 domain containing protein tyrosine phosphatase 2 antibody, SHP 2 antibody, SHP-2 antibody, Shp2 antibody, SHPTP2 antibody, SHPTP3 antibody, Syp antibody, Tyrosine-protein phosphatase non-receptor type 11 antibody

Fusion protein of human PTPN11

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

Antigen Affinity Purified

Signal Transduction

Fusion protein of Human PTPN11