TAF11 Antibody

TAF11

MGC:15243 antibody; p30 beta antibody; PRO2134 antibody; TAF antibody; TAF(II)28 antibody; TAF11 antibody; TAF11 RNA polymerase II TATA box binding protein (TBP) associated factor 28 kD antibody; TAF11_HUMAN antibody; TAF2I antibody; TAFII 28 antibody; TAFII-28 antibody; TAFII28 antibody; TFIID subunit p30 beta antibody; TFIID subunit p30-beta antibody; Transcription initiation factor TFIID 28 kDa subunit antibody; Transcription initiation factor TFIID subunit 11 antibody

Fusion protein of human TAF11

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene.

Antigen affinity purification

Epigenetics and Nuclear Signaling

Fusion protein of Human TAF11