AMACR Antibody

Polyclonal Antibody

AMACR

2 arylpropionyl CoA epimerase antibody, 2 methylacyl CoA racemase antibody, 2-methylacyl-CoA racemase antibody, Alpha methylacyl CoA racemase antibody, Alpha methylacyl Coenzyme A racemase antibody, Alpha methylacyl-CoA racemase deficiency, included antibody, Alpha-methylacyl-CoA racemase antibody, Amacr antibody, AMACR deficiency, included antibody, AMACR_HUMAN antibody, CBAS4 antibody, Da1-8 antibody, EC 5.1.99.4 antibody, Macr1 antibody, Methylacyl CoA racemase alpha antibody, RACE antibody, RM antibody

Fusion protein of human AMACR

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Antigen Affinity Purified

Signal Transduction

Fusion protein of Human AMACR