REN Antibody

Polyclonal Antibody

REN

Angiotensin forming enzyme antibody, Angiotensin forming enzyme precursor antibody, Angiotensinogenase antibody, Angiotensinogenase precursor antibody, FLJ10761 antibody, HNFJ2 antibody, REN antibody, Ren1 antibody, RENI_HUMAN antibody, Renin antibody, Renin precursor renal antibody

Fusion protein of human REN

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release, vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.

Antigen Affinity Purified

Cardiovascular

Fusion protein of Human REN