UBAP2L Antibody

Polyclonal Antibody

UBAP2L

FLJ42300 antibody, KIAA0144 antibody, NICE 4 antibody, NICE4 antibody, Protein NICE-4 antibody, Protein NICE4 antibody, Ubap2l antibody, Ubiquitin associated protein 2 like antibody, Ubiquitin-associated protein 2-like antibody, UBP2L_HUMAN antibody

Fusion protein of human UBAP2L

UBAP2L, also known as NICE4, is a protein that is ubiquitously expressed. Phosphorylated upon DNA damage, NICE4 contains one UBA domain and is expressed as 4 isoforms produced by alternative splicing events. The gene that encodes NICE4 maps to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3, 000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Antigen Affinity Purified

Cell Biology

Fusion protein of Human UBAP2L